Sexual performance may be a taboo topic for some people, but for men – and some women—it is as important as any health concern.
It can build and ruin relationships and self-esteem, and can even be a precursor to other problems, which are usually more alarming. For this reason, many men go to pharmacies to buy dapoxetine and sildenafil.
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What Are These Drugs For?
Sildenafil and dapoxetine are drugs for erectile dysfunction (ED) and premature ejaculation (PE), the causes of which are biological or psychological.
Type 2 diabetes leads to erectile dysfunction because poor blood sugar control can damage blood vessels and nerves. Premature ejaculation, in contrast, may stem from ED, anxiety, depression, and abnormal hormone levels.
Men on the lookout for drugs that boost sexual performance are often prescribed dapoxetine and Viagra. In a study by Chris McMahon, dapoxetine was found to increase and improve men’s control over their ejaculation (1).
There was a consensus among men and women that sexual satisfaction is highly associated with ejaculation, specifically its right timing. Thus, an option to available drugs and therapy was examined in clinical trials.
Results yielded that 26.7 percent of respondents perceived their partners’ control over ejaculation as “very good” with 30mg of dapoxetine. A higher percentage reported better satisfaction when their partners took 30mg of the drug.
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There was also a decrease in ejaculation-related distress and relationship problems after men were treated with dapoxetine.
Meanwhile, sildenafil, otherwise known as Viagra, is used long-term in oral therapy to treat impotence. Sildenafil has been proved to reduce blood pressure significantly and is rapidly absorbed in the bloodstream (2).
Patients also reported improvements in their erection, hardness, and overall sexual performance after being treated to 50 and 100mg of Sildenafil.
Medical studies have pointed out the efficacy of dapoxetine and Viagra, and testimonials continue to add to their reputation as two of the best pills for erectile dysfunction and premature ejaculation. But how much of these drugs can a person consume? Can these medications be taken together?
Can You Combine Dapoxetine and Sildenafil?
An experiment conducted in 2019 gave patients dapoxetine an hour or two before sex for a month. These patients also took Sildenafil during the experiment (3).
After four weeks, patients articulated their satisfaction in mixing dapoxetine and sildenafil for their treatment. Mild and transient side effects were likewise recorded: palpitation, headache, and flushing.
Doctors and pharmacists also warn patients with a history of heart attack to NOT take sildenafil and dapoxetine together. Nevertheless, a combined formulation of these drugs is available in the market, for as long as sildenafil is limited to 50mg, and dapoxetine is kept at 30mg.
An exception is made by Sunrise Remedies, who manufactured Super P-Force tablets, a drug that combines Viagra and dapoxetine, at 100 mg and 60 mg, respectively.
Like the individual Sildenafil and dapoxetine tablets, the combined ED and PE medication improves control over ejaculation and increases the interval between penetration and ejaculation. At the same time, the drug increases blood flow to the penis so the user can immediately get an erection.
Although two separate mechanisms target the disorders, the drug will only work when the patient is already aroused.
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People who have taken 100mg of sildenafil and 60 mg of dapoxetine have reported bouts of headache, nasal congestion, dizziness, nausea, insomnia, diarrhea, and indigestion. Thus, the safest formulation is 50mg/30mg.
Are Sildenafil and Dapoxetine Only for Older Men?
The clinical trial conducted to assess the efficacy and safety of Sildenafil and dapoxetine included men about 18 to 64 years old, who have no history of neurological conditions, surgeries, liver disease, renal problems, and epilepsy (4).
From a pragmatic point of view, adults can take the Viagra and dapoxetine combo, for as long they do not have the abovementioned health concerns.
Naturally, these drugs should only be taken for the purpose they serve. Sildenafil and dapoxetine for men are to be used solely as treatment and not as a regular drug to improve one’s erection or ejaculation.
Sildenafil and dapoxetine are taken before sex. Doctors and drug manufacturers strongly advise against the recreational use of these drugs.
What Are the Risks in Taking Them?
The combined effects of dapoxetine and sildenafil may contradict the effects of other drugs a person takes. Specifically, dapoxetine and sildenafil may not be compatible with SNRI antidepressants, treatments for HIV, antifungal and antibiotic drugs, and medicines for migraines.
Similarly, people taking nitrate medication, thioridazine, and NSAIDS should avoid mixing dapoxetine and sildenafil.
Aside from mild effects already discussed, too much sildenafil may lead to vision problems and photosensitivity (5). Other recorded side effects are cyanopsia, which gives users blue-tinged visions, although this is a rare occurrence. Viagra has also been found to cause damage to optic nerves and sudden loss of hearing.
Counteracting the treatment for ED is chances of heightened intraocular pressure and ventricular arrhythmias. Ironically, Sildenafil gives users a painful and long-lasting erection called priapism.
In contrast, there are milder side effects associated with long-term dapoxetine use. Even suddenly, breaking off from the treatment could lead to only minor issues.
Abrupt discontinuation of dapoxetine and other pills for men with premature ejaculation could lead to nausea, yawning, dizziness, and headache, already known side effects that occur in the duration of the treatment (6).
For this particular clinical observation, no severe effects were recorded. Expected adverse reactions were serotonin syndrome, aggressive behavior, and postural hypotension.
Are There Other Uses of Viagra and Dapoxetine?
Dapoxetine and viagra benefits are not limited to, enhancing sexual performance. Dapoxetine is originally an anti-depressant, while Sildenafil is also given to patients with COPD. Recent studies have proven the efficacy of the latter in treating upper respiratory problems.
Some manufacturers have combined these drugs, but only to a formulation of 50 mg (sildenafil) and 30mg (dapoxetine).
Summary
Dapoxetine and sildenafil are drugs used to treat premature ejaculation and erectile dysfunction. Unless doctors prescribe them for depression and COPD, these drugs must not be used regularly. Certain side effects, however mild, were recorded and could contradict the results of other medications taken by the patient.